Det danske Aarsmøde 1905

The Norwegian type-anaphor det

This paper gives a description of the Norwegian type anaphor det ('that') and proposes a formal representation of it in the HPSG framework. This identity-of-sense anaphor is interpreted as referring to a (new) set of entities of the same type as its antecedent. Its antecedent has to be either indefinite or a definite NP that is likely to introduce a brand new discourse referent. Whereas the typ...

Dmd059121 1890..1905

Subcutaneous injection is an important route of administration for therapeutic proteins that provides several advantages over other modes of parenteral delivery. Despite extensive clinical use, the exact mechanism underlying subcutaneous absorption of proteins is not completely understood, and the accuracy of prediction of absorption of biotherapeutics in humans remains unsatisfactory. This rev...

Det-extremal cubic bipartite graphs

Let G be a connected k–regular bipartite graph with bipartition V (G) = X ∪Y and adjacency matrix A. We say G is det–extremal if per(A) = |det(A)|. Det–extremal k–regular bipartite graphs exist only for k = 2 or 3. McCuaig has characterized the det–extremal 3–connected cubic bipartite graphs. We extend McCuaig’s result by determining the structure of det–extremal cubic bipartite graphs of conne...

Dmd065763 1905..1916

Montelukast has been recommended as a selective in vitro and in vivo probe of cytochrome P450 (P450) CYP2C8 activity, but its selectivity toward this enzyme remains unclear. We performed detailed characterization of montelukast metabolism in vitro using human liver microsomes (HLMs), expressed P450s, and uridine 59-diphospho-glucuronosyltransferases (UGTs). Kinetic and inhibition experiments pe...

Phoebus A. Levene, 1905